Experts Say... http://www.extrahandsforals.org/mt/ You have questions, lots of them. It would take the doctor a week to answer them, and he or she does not have all the answers. Fortunately, most of your questions have been answered before. "Experts Say..." is a collection of hundreds of articles on topics you want to learn more about. They are displayed below by the date they were posted. You may find it easier to browse by topics, listed on the right side. en-us 2008-10-28T14:40:39-06:00 Gene Discovery Could Help ALS Patients http://www.extrahandsforals.org/mt/archives/000751.html (Ivanhoe Newswire) -- Scientists are one step closer to understanding how to treat and repair diseases of the nervous system, such as amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease. According to a new study, researchers at the University of... ALS Research Editor 2008-10-28T14:40:39-06:00 Focusing on glial cells to overcome an intractable disease, ALS http://www.extrahandsforals.org/mt/archives/000750.html Amyotrophic lateral sclerosis (ALS) is a devastating disease, gradually causing paralysis of the muscles in the hand and leg. The discovery by Koji Yamanaka and colleagues at the Brain Science Institute that the glial cells cause damage to the nerve... ALS Research Editor 2008-10-28T14:37:22-06:00 TDP-43 expression in mouse models of amyotrophic lateral sclerosis and spinal muscular atrophy http://www.extrahandsforals.org/mt/archives/000749.html Redistribution of nuclear TAR DNA binding protein 43 (TDP-43) to the cytoplasm and ubiquitinated inclusions of spinal motor neurons and glial cells is characteristic of amyotrophic lateral sclerosis (ALS) pathology. Recent evidence suggests that TDP-43 pathology is common to sporadic... ALS Research Editor 2008-10-28T14:30:26-06:00 Outnumbering Unhealthy Cells with Healthy Ones Helps Sustain Breathing in ALS Mice http://www.extrahandsforals.org/mt/archives/000748.html GEN News Highlights Scientists say that transplanting a new line of stem cell like cells into rat models shifts key signs of neurodegenerative disease in general and those of amyotrophic lateral sclerosis (ALS) in particular. They found that it slowed... ALS Research Editor 2008-10-23T15:47:30-06:00 Astrocyte replacement shows promise in a rat model of ALS http://www.extrahandsforals.org/mt/archives/000747.html Stem cell approaches for the treatment of neurodegenerative diseases has become a very attractive option. In amyotrophic lateral sclerosis (ALS), the cells affected in the disease, the motor neurons, have extremely long processes that need to be appropriately connected with... ALS Research Editor 2008-10-22T17:20:12-06:00 Gene find sheds light on motor neuron diseases like ALS http://www.extrahandsforals.org/mt/archives/000746.html Scientists have identified a gene in mice that plays a central role in the proper development of one of the nerve cells that goes bad in amyotrophic lateral sclerosis, or Lou Gehrig's disease, and some other diseases that affect our... ALS Research Editor 2008-10-22T17:15:57-06:00 Stem Cells May Act as “Trojan Horse” to Deliver Gene Therapy to Injured Central Nervous System http://www.extrahandsforals.org/mt/archives/000745.html Newswise — Amyotrophic lateral sclerosis (ALS) researchers at The Methodist Hospital in Houston have shown that transplanted bone marrow stem cells can attach themselves to injured areas in the brain or spinal cord, possibly providing a way to deliver future... ALS Research Editor 2008-10-18T14:10:43-06:00 FDA: Statins don't increase ALS risk http://www.extrahandsforals.org/mt/archives/000743.html Sept. 30 (UPI) -- The U.S. Food and Drug Administration says it has determined statins do not increase the incidence of amyotrophic lateral sclerosis, or Lou Gehrig's Disease. The FDA's review began in 2007 after the agency received a higher-than-expected... ALS Research Editor 2008-09-30T14:08:38-06:00 T-cells Show Promise for ALS, Neurodegenerative Disease Therapies http://www.extrahandsforals.org/mt/archives/000741.html Newswise — A type of white blood cell that is important to the immune system may provide hope for future new therapies for amyotrophic lateral sclerosis (ALS), as well as other neurodegenerative diseases, according to a study published online today... ALS Research Editor 2008-09-24T12:56:07-06:00 Research sees new ALS hope http://www.extrahandsforals.org/mt/archives/000740.html by Jim O'Connell Wednesday, September 17, 2008 University of Wisconsin researchers have discovered a breakthrough in the treatment of amyotrophic lateral sclerosis, better known as Lou Gehrig’s Disease. The team, led by associate scientist Masatoshi Suzuki and neurology professor Clive... ALS Research Editor 2008-09-17T13:23:47-06:00 Nerve cells grown from new-style stem cells http://www.extrahandsforals.org/mt/archives/000739.html Ordinary skin cells taken from patients with a fatal and incurable nerve disease have been transformed into nerve cells in a first step toward treating them, US researchers reported. They transformed the cells from two patients with amyotrophic lateral sclerosis... ALS Research Editor 2008-09-15T12:58:16-06:00 The ALS Association to Support Trial of Lithium http://www.extrahandsforals.org/mt/archives/000738.html by Richard Robinson The ALS Association is funding a major clinical trial to determine if lithium can slow disease progression in patients in the early stages of ALS. The study builds on earlier promising results from preclinical research and a... Clinical Trials Editor 2008-08-28T17:02:42-06:00 Predicting patient survival from protein stability and aggregation propensity http://www.extrahandsforals.org/mt/archives/000736.html Amyotrophic Lateral Sclerosis (ALS), also known in America as Lou Gehrig's disease, is a fatal neurodegenerative disease that has no effective treatment. While it is well known that specific genetic mutations can cause the condition, how the changed genes produce... ALS Research Editor 2008-08-11T15:08:04-06:00 Computers Predict ALS http://www.extrahandsforals.org/mt/archives/000734.html (Ivanhoe Newswire) -- A technique rarely used to analyze animal behavior may be the next step in fighting the most common motor neuron disease. Psychologists are using their original data-mining software to detect signs of amyotrophic lateral sclerosis (ALS), a... Diagnosis Editor 2008-08-05T15:57:40-06:00 Harvard, Columbia Researchers Make Stem Cell Breakthrough http://www.extrahandsforals.org/mt/archives/000732.html Advance will aid search for treatments to a variety of diseases, researchers say By CLIFFORD M MARKS Scientists from Harvard and Columbia announced Thursday the creation of the first patient-specific stem cell line from humans afflicted with a genetic disease,... ALS Research Editor 2008-08-01T16:04:59-06:00